Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors during the central nervous technique, conolidine modulates alternate molecular targets. A Science Innovations study found that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://paxtonsnjfx.dm-blog.com/38999873/not-known-facts-about-conoldine-alternative-natural-pain-relief