There is a release of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors in the dorsal horn to minimize afferent agony transmission and develop analgesia. Thus, medications like clonidine that goal alpha-two receptors can influence the transmission of ache. Clonidine treats high hypertension by stimulating α2 https://what-is-kratom07283.theblogfairy.com/31414886/the-2-minute-rule-for-onolidine